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	<title>Cheney Research &#187; Calcium</title>
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		<title>More on Vitamin D3 and CFS</title>
		<link>http://www.cheneyresearch.com/2009/12/more-on-vitamin-d3-and-cfs</link>
		<comments>http://www.cheneyresearch.com/2009/12/more-on-vitamin-d3-and-cfs#comments</comments>
		<pubDate>Thu, 24 Dec 2009 01:24:41 +0000</pubDate>
		<dc:creator>pcheney</dc:creator>
				<category><![CDATA[Hormones in CFS]]></category>
		<category><![CDATA[azoles]]></category>
		<category><![CDATA[Calcium]]></category>
		<category><![CDATA[NADPH]]></category>
		<category><![CDATA[NF Kappa B]]></category>
		<category><![CDATA[P450]]></category>
		<category><![CDATA[Vitamin D3]]></category>

		<guid isPermaLink="false">http://www.cheneyresearch.com/?p=512</guid>
		<description><![CDATA[Vitamin D3 is regulated by P450 enzyme systems that are in turn decoupled due to low NADPH levels in CFS.  This raises important questions regarding the reasons that may underlie low D3 levels typical for most CFS cases.  The finding of increased intracellular calcium by UK investigators may also play into the reasons for finding low D3 in CFS.  Given these deeper issues that may underlie D3 levels suggests that aggressive D3 therapy may not be the best course of action in CFS.  D3 is a highly regulated pro-hormone and there could be good reasons for it to be down-regulated in CFS.]]></description>
			<content:encoded><![CDATA[<p>The effect of vitamin D3 on the echocardiograph ETM in CFS, but not in controls, shows a transient and negative IVRT backflash.  I would not call this effect an &#8220;oxygen toxic effect&#8221; but rather a negative redox shift caused </p>
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