A paucity of autoimmune disease and hypertension in CFS

May 3rd, 2009, published in Chronic Fatigue Syndrome

It is interesting that T-cell activation is such as big part of CFS and hence TGF Beta-1 activation in response to T-cell activation.  Yet,  there is little true autoimmune disease seen in CFS as distinct from autoantibody formation without organ destruction which is more common.  Do you suppose TGF Beta-1 activation is the reason for such low autoimmune disease or despite it as there is some other reason?  Also, there is a significant paucity of hypertension seen in my CFS cohort.  Hypertension  is seen in less than 1% in my practice and I suspect strikingly different than a normal internal medicine practice which was 40% or more for me some 20+ years ago.

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Copyright 2009 - Paul R. Cheney MD, PhD
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